Asafetida
Title: Asafetida
CAS Registry Number: 9000-04-8
Additional Names: Devil's dung; food of the gods; asafoetida; asant
Literature References: Gum-resin obtained as an exudation of the decapitated rhizome and roots of Ferula assafoetida L., F. foetida Regel and some other species of Ferula, Umbelliferae. Habit. Iran, Turkestan, Afghanistan. Constit. 6-17% ethereal oil; 40-60% resin, consisting of ester of asaresinotannol and ferulic acid; pinene, vanillin, about 25% gum. Three sulfur-containing compounds isolated from asafetida resin are: 1-methylpropyl 1-propenyl disulfide, 1-(methylthio)propyl 1-propenyl disulfide and 1-methylpropyl 3-(methylthio)-2-propenyl disulfide; the latter two have pesticidal properties. Studies of various constituents: B├ęzanger-Beauquesne, Chosson, Ann. Pharm. Fr. 16, 665 (1958); Caglioti et al., Helv. Chim. Acta 41, 2278 (1958); 42, 2557 (1959). Isoln and structure elucidation of three sulfur-containing components: H. Naimie et al., Collect. Czech. Chem. Commun. 37, 1166 (1972). Synthesis and configuration of sulfur-containing constituents: J. Meijer, P. Vermeer, Rec. Trav. Chim. 93, 242 (1974); A. Kjac et al., Acta Chem. Scand. B 30, 137 (1976). Review: Howes, Econ. Bot. 4, 313 (1950); Subrahmanyam et al., J. Sci. Ind. Res. 13A, 382-386 (1954).
Properties: Soft mass or irregular lumps or "tears"; garlic-like odor; bitter acrid taste. When triturated with water, it makes a milky emulsion.
Use: In India, Iran, etc., as condiment and flavoring for foods; an ingredient in Worcestershire sauce. A 2% suspension as repellent against dogs, cats, rabbits, deer.
Therap-Cat: Carminative; expectorant.
Therap-Cat-Vet: Has been used as a carminative, and externally to prevent bandage chewing by dogs.

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