Dimefox
Title: Dimefox
CAS Registry Number: 115-26-4
CAS Name: Tetramethylphosphorodiamidic fluoride
Additional Names: tetramethyldiamidophosphoric fluoride; bis(dimethylamido)phosphoryl fluoride; fluophosphoric acid di(dimethylamide); bisdimethylaminofluorophosphine oxide; bis(dimethylamido)fluorophosphate; Pestox XIV
Molecular Formula: C4H12FN2OP
Molecular Weight: 154.12
Percent Composition: C 31.17%, H 7.85%, F 12.33%, N 18.18%, O 10.38%, P 20.10%
Literature References: Prepd by fluorination of bis(dimethylamido)phosphoryl chloride: Schrader, Angew. Chem. Suppl. 62, 18 (1951); BIOS Final Report No. 714 (1947); Holmsted, Acta Physiol. Scand. Suppl. 90, 33 (1951); Heap, Saunders, J. Chem. Soc. 1948, 1313; GB 692446 (1953); McCombie et al., US 2489917 (1949). Toxicity data: A. J. Okinaka et al., J. Pharmacol. Exp. Ther. 112, 231 (1954). Review: Kilby, Chem. Ind. (London) 1953, 856.
Properties: Liquid. Fishy odor. d420 1.1151. bp4.0 67°; bp15 86°. nD20 1.4267. Freely sol in water, ether, benzene. Aq solns are stable. LD50 in rats (mg/kg): 5.0 i.p.; 7.5 orally (Okinaka).
Boiling point: bp4.0 67°; bp15 86°
Index of refraction: nD20 1.4267
Density: d420 1.1151
Toxicity data: LD50 in rats (mg/kg): 5.0 i.p.; 7.5 orally (Okinaka)
CAUTION: A highly toxic cholinesterase inhibitor. Symptoms similar to parathion, q.v.: Clinical Toxicology of Commercial Products, R. E. Gosselin et al., Eds. (Williams & Wilkins, Baltimore, 5th ed., 1984) Section II, p 299.
Use: Insecticide; acaricide.

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