Tropicamide
Title: Tropicamide
CAS Registry Number: 1508-75-4
CAS Name: N-Ethyl-a-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide
Additional Names: N-ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide; N-ethyl-N-(g-picolyl)tropamide
Trademarks: Mydriacyl (Alcon); Mydriaticum (Merck & Co.)
Molecular Formula: C17H20N2O2
Molecular Weight: 284.35
Percent Composition: C 71.81%, H 7.09%, N 9.85%, O 11.25%
Literature References: Ophthalmic anticholinergic. Prepn: Rey-Bellet, Spiegelberg, US 2726245 (1955 to Hoffmann-La Roche). Comprehensive description: K. W. Blessel et al., Anal. Profiles Drug Subs. 3, 565-580 (1974).
Properties: Crystals, mp 96-97°. uv max (0.025 mg/ml in 0.1N HCl): 254 nm (e 5.1´103).
Melting point: mp 96-97°
Absorption maximum: uv max (0.025 mg/ml in 0.1N HCl): 254 nm (e 5.1´103)
Therap-Cat: Mydriatic.
Therap-Cat-Vet: Mydriatic.
Keywords: Antimuscarinic; Mydriatic.

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