Tybamate
Title: Tybamate
CAS Registry Number: 4268-36-4
CAS Name: Butylcarbamic acid 2-[[(aminocarbonyl)oxy]methyl]-2-methylpentyl ester
Additional Names: carbamate of 2-(hydroxymethyl)-2-methylpentyl ester of butylcarbamic acid; N-butyl-2-methyl-2-propyl-1,3-propanediol dicarbamate; 2-methyl-2-propyltrimethylene butylcarbamate carbamate
Trademarks: Nospan (Johnsons); Solacen (Wallace Labs.); Tybatran (Robins)
Molecular Formula: C13H26N2O4
Molecular Weight: 274.36
Percent Composition: C 56.91%, H 9.55%, N 10.21%, O 23.33%
Literature References: Prepd from 2-methyl-2-propyl-3-hydroxypropyl carbamate + butyl isocyanate: Berger, Ludwig, US 2937119 (1960 to Carter Prod.). Comprehensive description: P. Reisberg et al., Anal. Profiles Drug Subs. 4, 494-515 (1975).
Properties: Crystals from 1,1,2-trichloroethane + hexane (1:2), mp 49-51°, bp0.06 150-152°.
Melting point: mp 49-51°
Boiling point: bp0.06 150-152°
Therap-Cat: Anxiolytic.
Keywords: Anxiolytic; Carbamates.

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