Moperone
Title: Moperone
CAS Registry Number: 1050-79-9
CAS Name: 1-(4-Fluorophenyl)-4-[4-hydroxy-4-(4-methylphenyl)-1-piperidinyl]-1-butanone
Additional Names: p-fluoro-4-(4¢-hydroxy-4¢-p-tolylpiperidino)butyrophenone; p-fluoro-4-(4¢-hydroxy-4¢-p-methylphenylpiperidino)butyrophenone; 1-(3¢-p-fluorobenzoylpropyl)-4-hydroxy-4-p-tolylpiperidine; w-(4-hydroxy-4-p-tolylpiperidino)-p-fluorobutyrophenone; methylperidol
Manufacturers' Codes: R-1658
Molecular Formula: C22H26FNO2
Molecular Weight: 355.45
Percent Composition: C 74.34%, H 7.37%, F 5.34%, N 3.94%, O 9.00%
Literature References: Prepn: Janssen et al., J. Med. Pharm. Chem. 1, 281 (1959); Janssen, GB 881893 (1961).
Properties: Crystals, mp 118-119.5°. uv max: 246.5 nm (e 12200).
Melting point: mp 118-119.5°
Absorption maximum: uv max: 246.5 nm (e 12200)
 
Derivative Type: Hydrochloride
CAS Registry Number: 3871-82-7
Trademarks: Luvatren (Cilag-Chemie)
Molecular Formula: C22H26FNO2.HCl
Molecular Weight: 391.91
Percent Composition: C 67.42%, H 6.94%, F 4.85%, N 3.57%, O 8.16%, Cl 9.05%
Properties: Crystals from isopropyl ether, mp 216-218°.
Melting point: mp 216-218°
 
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Butyrophenones.

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